If your doctor has prescribed this medication, take it as directed. Administration of ZYLOPRIM allopurinol generally results in a fall in both serum and urinary uric acid within 2 to 3 days. The degree of this decrease can be manipulated almost at will since it is dose-dependent. A week or more of treatment with ZYLOPRIM allopurinol may be required before its full effects are manifested; likewise, uric acid may return to pretreatment levels slowly usually after a period of 7 to 10 days following cessation of therapy. This reflects primarily the accumulation and slow clearance of oxipurinol. Low magnesium levels in your body. This problem can be serious. Low magnesium can happen in some people who take a PPI medicine for at least 3 months. If low magnesium levels happen, it is usually after a year of treatment. You may or may not have symptoms of low magnesium.
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